The Virgin of the Annunciation by Antonello da Messina.

He spent ages adjusting the position of Billie Whitelaw’s hands on her upper arms, creating, whether he recognised it or not, a striking parallel with the picture of The Virgin of the Annunciation by Antonelle da Messina which had impressed him so much in the Alte Pinakotek in Munich forty years before. Yet while the face of the virgin is one of calmness and serenity, Beckett’s image is transformed into a tortured soul, her hands claw-like, her face full of pain and distress.

James Knowlson
Damned to Fame: The Life of Samuel Beckett